DEBITUS Cécile
Cécile Debitus
Directeur de recherche
Responsable équipe EIMS
Thématiques de recherche :
Invertébrés benthiques (éponges, ascidies) : biodiversité et biogéographie ; éponges bathyales
Substances naturelles d’origine marine : chimiotaxonomie, écologie chimique, activités biologiques et applications (aquaculture et santé humaine)
Adresse : IRD - BP529 - 98713 Papeete - Polynésie française
tel : +689 40 47 42 03
courriel : cecile.debitus@ird.fr
Publications
2015
ACL :
Mai T., Tintillier F., Lucasson A., Moriou C., Bonno E., Petek S., Magré K., Al Mourabit A., Saulnier D., Debitus C., Quorum sensing inhibitors from Leucetta chagosensis Dendy, 1863, Lett. Appl. Microbiol. 2015, 61:311-317
Wecker P., Fournier A., Bosserelle P., Debitus C., Lecellier G., Berteaux-Lecellier V., Dinoflagellate diversity among nudibranchs and sponges from French Polynesia: insights into associations and transfer, C. R. Biologies 2015, 338:278-83.
Schroif-Grégoire C., Appenzeller J., Debitus C., Zaparucha A., Al-Mourabit A., Debromokeramadine from the marine sponge Agelas cf. mauritiana : isolation and short regioselective and flexible synthesis, Tetrahedron, 2015, 3609-3613
Monniot F. & Debitus C., Redescription of Herdmania papietensis Herdman, 1882 (Ascidiacea, Pyuridae) from Polynesia. Zootaxa, 2015, 3911: 294–300
Laville R., Nguyen T.B., Moriou C., Petek S., Debitus C., Al Mourabit A., Marine natural occuring 2, 5-diketopiperazines : isolation, synthesis and optical properties, Heterocycles 2015, 90:1351-1366
C-ACTI :
Debitus C. Marine benthic invertebrates: biodiversity, interactions and chemodiversity evaluation for a sustainable use in the field of aquaculture, pearl farming and human health, The 7th edition of the Rendez-Vous de Concarneau: where Industry meets Science in marine Biotechnology, Concarneau, 10/16/2015
2014
ACL :
Festa C., Cassiano C., D’Auria M.V., Debitus C., Monti M.C., De Marino S.Scalarane sesterterpenes from Thorectidae sponges as inhibitors of TDP-43 nuclear factor, Org. Biomol.Chem. 2014, 12:8646-55.
C-ACTI :
Debitus C., From the Coral sea to Central Pacific for marine natural products, 5th Regional Access and Benefit Sharing Workshop for the Pacific, Sydney, 10-13 November 2014
C-COM :
Mai T., Tintillier F., Petek S., Moriou C., Al Mourabit A., Saulnier D., Debitus C. Pomare project, first results on marine invertebrates quorum sensing inhibitors, The 6th edition of the "Rendez-Vous de Concarneau: where Industry meets Science in marine Biotechnology" 9-10/10/2014
Debitus C. &Johnson D., signalement de Gibberichthys sp. au large de Tahiti, SFI infos, 71, oct 2014
OUV :
Debitus C. & Kornprobst J.-M., Pigments of living fossil crinoids, in Outstanding marine molecules: Chemistry, Biology, Analysis, First Edition. Edited by Stephane La Barre and Jean-Michel Kornprobst. Wiley-VCH Verlag GmbH & Co. KGaA, 2014 , 163-170
Debitus C. & Guezennec J., Pharmacologie des organismes marins des récifs coralliens, in Hermes sciences publications, coll. Mer & océans, 2014, 6:113-148
Debitus C. & Guézennec J., 2014. Pharmacology of Reef Marine Organisms, in "Development of Marine Resources", Seas and Oceans Set, A.Monaco and P. Prouzet (Edit), ISTE - John WILEY & Sons Publis., 3, 117-156.
2013
ACL :
Hall K.A., Sutcliff P.R., Hooper J.N.A., Alencar A., Vacelet J., Pisera A., Petek S., Folcher E., Butscher J., Orempuller J., Debitus C., Affinities of sponges (Porifera) of the Marquesas and Society Islands, French Polynesia, Pacific Science 2013, 67:493-511
C-ACTI :
D'Auria M. V., De Marino S., Sepe V., Zampella A., Bifulco G., Renga B., D'Amore C., Fiorucci S., Debitus C. Marine natural products as modulators of nuclear receptors. Planta Medica, 2012, 78, 1051.
Boufridi A., Debitus C., Maciuk A., Evanno L., Poupon E. Ilimaquinone and minor metabolites from Polynesian marine sponges : isolation and ecology. Planta Medica, 2012, 78, 1071.
Doumenge F., Debitus C., Sautel F., Molécules à visée pharmaceutique. De la mer aux laboratoires, sciences au sud, oct 2013
C-AFF :
Debitus C., Pisera A., M. Ekins, Curvat X., Hertrich L., Al Mourabit A., First record of lithistid sponges from the submarine caves from the Nuku Hiva (Marquesas Islands) and Tahiti Iti (Tahiti), French Polynesia, 9th World Sponge Conference, Fremantle (Australia) 4-9 november 2013
Hall K., Ekins M., Sutcliff P., Hooper J., Petek S., Folcher E., Debitus C., The diversity of sponges form French Polynesia, 9th World Sponge Conference, Fremantle (Australia) 4-9 november 2013
AP :
Debitus C. Les éponges de Polynésie française, 50 ans de recherche pour le développement en Polynésie française, IRD éditions, 2013, pp121-129
Debitus C. (2013) TAHITI ITI cruise, Alis R/V, http://dx.doi.org/10.17600/13100040
Debitus C. (2013) TUHAA PAE 2013 cruise, Alis R/V, http://dx.doi.org/10.17600/13100030
2012
ACL :
Festa.C, De Marino S., D'Auria M.V., Monti M.C., Bucci M., Velleco V., Debitus C., Zampella A., Anti-inflammatory of the sponge Theonella swinhoei, Tetrahedron 2012, 68:2851-2853
Sorres J., Martin M. T., Petek S., Levaique H., Cresteil T., Ramos S., Thoison O., Debitus C., Al-Mourabit A. Pipestelides A-C: Cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra. J. Nat. Prod. 2012, 75:759-763
Sepe V., Ummarino R., D’Auria M.V., Chini M.G., Bifulco G., Renga B., D’Amore C., Debitus C., Fiorucci S., Zampella A., Conicasterol E, a small heterodimer partner sparing farnesoid X receptor endowed with a pregnane X receptor agonistic activity frome the marine sponge Theonella swinhoei J. Med. Chem. 2012, 55: 84-93
Mani L., Jullian V., Mourkazel B., Valentin A., Dubois J., Cresteil T., Folcher E., Hooper J.N.A., Erpenbeck D., Aalbersberg W., Debitus C. New antiplasmodial bromotyrosine derivatives from Suberea ianthelliformis Ledenfelds, 1888, Chem. Biodiv. 2012, 9:1436:1451
Farokhi F., Wielgosz-Collin G., Robic A., Debitus C., Malleter M., Roussakis C., Kornprobst J.M., Barnathan G., Antiproliferative activity against non-small cell lung cancer of two O-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeve, Eur. J. Med. Chem. 2012, 49:406-410
Erpenbeck D., Hooper J.N.A., Bonnard I., Sutcliffe P., Chandra Mayuri, Perio Pierre, Wolff C., Banaigs B., Wörheide G., Debitus C., Petek S., Evolution, radiation and chemotaxonomy of Lamellodysidea, a demosponge genus with anti-plasmodial metabolites, Mar. Biol. 2012, 159:1119-1127
C-ACTI :
D'Auria M. V., De Marino S., Sepe V., Zampella A., Bifulco G., Renga B., D'Amore C., Fiorucci S., Debitus C. Marine natural products as modulators of nuclear receptors. Planta Medica, 2012, 78, 1051.
Boufridi A., Debitus C., Maciuk A., Evanno L., Poupon E. Ilimaquinone and minor metabolites from Polynesian marine sponges : isolation and ecology. Planta Medica, 2012, 78, 1071.
Projets Scientifiques
ANR Netbiome POMARE (2012-2016)
CdP Etat-Polynésie BioPolyVal (2013-2015)
QSI (2013)
Participation à projets
- Symbiocomp (Labex Corail 2013-2014)
- Cdp Etat Polynésie française Marquesas (2010-2012)